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Does the embryo cleavage pattern and rate of blastocyst formation differ between normal weight and obese women undergoing IVF?
Can non-invasive imaging with fluorescence lifetime imaging microscopy (FLIM) detect metabolic differences in euploid versus aneuploid human blastocysts?
Increased demand for in vitro fertilization (IVF) due to socio-demographic trends, and supply facilitated by new technologies, converged to transform the way a substantial proportion of humans reproduce.
Japanese scientists have investigated and shown the role of inhibitor 130 (Gp130) in the embryo implantation process. Gp130 is a part of the Leukemia inhibitory factor (LIF) receptor. The latter has its own importance in the signaling system of 17β-estradiol (E2). The generated knockout of Gp130 fails the estrogen- and progesterone-responsive gene expression.
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