The MIRI Time-Lapse Incubator is a multiroom incubator with a built-in camera and microscope. Designed and manufactured in EU, the MIRI Time-Lapse Incubator provides high quality time-lapse images of embryos developing in "real-time" without having to remove the embryos from the safety of the incubation chamber for manual microscopy. Time-lapse embryo monitoring provides detailed morphokinetic data throughout embryo development, which is not available on routine spot microscopic evaluation. This allows all important events to be observed, helping to identify healthy embryos with the highest probability of implantation, with the aim of achieving higher pregnancy rates.
The compartments are separate from one another and do not affect each other's temperatures in any way. There is no effect on the remainder of the system from any disruption in one chamber, such as a temperature reduction after opening the lid. The temperature in the culture chambers and the lids can be controlled and regulated as well. The top and the bottom of each compartment are separated with a PET layer so that the lid temperature would not affect the bottom. For validation purposes, each compartment has a PT-1000 sensor built-in. The circuitry is separated from the unit's electronics, so it remains a genuinely separate validation system.
The incubator also features a recirculated gas system where gas is continuously put into the compartment and taken out at the same rate. Gas is cleaned via a 254 nm UVC light with direct gas contact between the bulb and gas. The UVC light has filters that inhibit any 185 nm radiation that would produce dangerous ozone.
The incubator needs 100% CO and 100% N2 to control the CO and O concentrations in the culture chambers. A dual-beam infra-red CO sensor with extremely low drift rates controls the CO levels. On the other hand, a chemical, medical-grade oxygen sensor controls the levels of the O in the system.